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Utilizing digital pathology and immunohistochemistry of p53 as an adjunct to molecular testing in myeloid disorders

TP53 mutation status guides early therapeutic decisions in the treatment of clonal myeloid disorders and serves as a simple means of monitoring response to treatment. We aim here to develop a standardized protocol for evaluating TP53 mutation status in myeloid disorders using immunohistochemistry as...

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Detalles Bibliográficos
Autores principales: Rogers, Kai J., Abukhiran, Ibrahim M., Syrbu, Sergei, Tomasson, Michael, Bates, Melissa, Dhakal, Prajwal, Bhagavathi, Sharathkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031312/
https://www.ncbi.nlm.nih.gov/pubmed/36970330
http://dx.doi.org/10.1016/j.acpath.2022.100064