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ADP receptor P2Y12 is the capstone of the cross-talk between Ca(2+) mobilization pathways dependent on Ca(2+) ATPases sarcoplasmic/endoplasmic reticulum type 3 and type 2b in platelets

BACKGROUND: Blood platelet Ca(2+) stores are regulated by 2 Ca(2+)-ATPases (SERCA2b and SERCA3). On thrombin stimulation, nicotinic acid adenosine dinucleotide phosphate mobilizes SERCA3-dependent stores, inducing early adenosine 5‘-diphosphate (ADP) secretion, potentiating later SERCA2b-dependent s...

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Detalles Bibliográficos
Autores principales: Feng, Miao, Hechler, Béatrice, Adam, Frédéric, Gachet, Christian, Eckly, Anita, Kauskot, Alexandre, Denis, Cécile V., Bryckaert, Marijke, Bobe, Régis, Rosa, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031336/
https://www.ncbi.nlm.nih.gov/pubmed/36970741
http://dx.doi.org/10.1016/j.rpth.2022.100004