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ADP receptor P2Y12 is the capstone of the cross-talk between Ca(2+) mobilization pathways dependent on Ca(2+) ATPases sarcoplasmic/endoplasmic reticulum type 3 and type 2b in platelets
BACKGROUND: Blood platelet Ca(2+) stores are regulated by 2 Ca(2+)-ATPases (SERCA2b and SERCA3). On thrombin stimulation, nicotinic acid adenosine dinucleotide phosphate mobilizes SERCA3-dependent stores, inducing early adenosine 5‘-diphosphate (ADP) secretion, potentiating later SERCA2b-dependent s...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031336/ https://www.ncbi.nlm.nih.gov/pubmed/36970741 http://dx.doi.org/10.1016/j.rpth.2022.100004 |