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Enriched environment can reverse chronic sleep deprivation-induced damage to cellular plasticity in the dentate gyrus of the hippocampus

OBJECTIVE: We studied whether enriched environment (EE), a classic epigenetics paradigm, can prevent cellular plasticity damage caused by chronic sleep deprivation (SD). METHODS: We performed SD in mice by a modified multi-platform method (MMPM). Mice in the SD group were deprived of sleep for 18 h...

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Detalles Bibliográficos
Autores principales: Shixing, Xue, Xueyan, Hou, Yuan, Ren, Wei, Tang, Wei, Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031502/
https://www.ncbi.nlm.nih.gov/pubmed/36969794
http://dx.doi.org/10.1515/tnsci-2022-0280