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CD80 DNA methylation and single-nucleotide polymorphism associated with clopidogrel response: a whole-genome DNA methylation analysis in acute coronary syndrome

BACKGROUND: Dual antiplatelet therapy with clopidogrel and aspirin is the primary treatment for patients who undergo percutaneous coronary intervention. However, the interindividual difference in clopidogrel response is remarkable, and high on-treatment platelet reactivity (HTPR) can increase the ri...

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Detalles Bibliográficos
Autores principales: Song, Pei-Yuan, Li, Mu-Peng, Peng, Li-Ming, Chen, Xiao-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031538/
https://www.ncbi.nlm.nih.gov/pubmed/36970128
http://dx.doi.org/10.1016/j.rpth.2023.100093