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Protective effects of an electrophilic metabolite of docosahexaenoic acid on UVB-induced oxidative cell death, dermatitis, and carcinogenesis

Docosahexaenoic acid (DHA), a representative omega-3 (ω-3) polyunsaturated fatty acids, undergoes metabolism to produce biologically active electrophilic species. 17-Oxo-DHA is one such reactive metabolite generated from DHA by cyclooxygenase-2 and dehydrogenase in activated macrophages. The present...

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Detalles Bibliográficos
Autores principales: Kim, Seong Hoon, Lee, So Eui, Kim, Su-Jung, Fang, Xizhu, Hur, Jihyeon, Sozen, Erdi, Özer, Nesrin Kartal, Kim, Kwang Pyo, Surh, Young-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031545/
https://www.ncbi.nlm.nih.gov/pubmed/36934646
http://dx.doi.org/10.1016/j.redox.2023.102666