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Tebentafusp: a first-in-class treatment for metastatic uveal melanoma

Tebentafusp is a first-in-class immunotherapy agent that comprises an engineered T-cell receptor targeting a gp100 epitope presented by human leukocyte antigen-A*02:01 cells, fused to an anti-CD3 single-chain variable fragment. Tebentafusp is both the first bispecific T-cell engager to show efficacy...

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Detalles Bibliográficos
Autores principales: Howlett, Sarah, Carter, Thomas J., Shaw, Heather M., Nathan, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031621/
https://www.ncbi.nlm.nih.gov/pubmed/36970111
http://dx.doi.org/10.1177/17588359231160140