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Intraosseous transplant of dystrophin expressing chimeric (DEC) cells improves skeletal muscle function in mdx mouse model of Duchenne muscular dystrophy

INTRODUCTION: We previously reported that systemic delivery of dystrophin expressing chimeric (DEC) cells of normal (wt) and dystrophin-deficient (mdx) myoblast (MB) or mesenchymal stem cell (MSC) origin restored dystrophin expression and improved cardiac function in the mdx mouse model of Duchenne...

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Detalles Bibliográficos
Autores principales: Malik, Mohammad, Siemionow, Maria, Cwykiel, Joanna, Heydemann, Ahlke, Garcia-Martinez, Jesus, Siemionow, Krzysztof, Szilagyi, Erzsebet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031668/
https://www.ncbi.nlm.nih.gov/pubmed/36967847
http://dx.doi.org/10.5114/aic.2021.110990