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Optimized genetic code expansion technology for time‐dependent induction of adhesion GPCR‐ligand engagement

The introduction of an engineered aminoacyl–tRNA synthetase/tRNA pair enables site‐specific incorporation of unnatural amino acids (uAAs) with functionalized side chains into proteins of interest. Genetic Code Expansion (GCE) via amber codon suppression confers functionalities to proteins but can al...

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Detalles Bibliográficos
Autores principales: Streit, Marcel, Hemberger, Mareike, Häfner, Stephanie, Knote, Felix, Langenhan, Tobias, Beliu, Gerti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031756/
https://www.ncbi.nlm.nih.gov/pubmed/36870000
http://dx.doi.org/10.1002/pro.4614