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Optimized genetic code expansion technology for time‐dependent induction of adhesion GPCR‐ligand engagement
The introduction of an engineered aminoacyl–tRNA synthetase/tRNA pair enables site‐specific incorporation of unnatural amino acids (uAAs) with functionalized side chains into proteins of interest. Genetic Code Expansion (GCE) via amber codon suppression confers functionalities to proteins but can al...
Autores principales: | Streit, Marcel, Hemberger, Mareike, Häfner, Stephanie, Knote, Felix, Langenhan, Tobias, Beliu, Gerti |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031756/ https://www.ncbi.nlm.nih.gov/pubmed/36870000 http://dx.doi.org/10.1002/pro.4614 |
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