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Circ_0002715 promotes the development of osteoarthritis through regulating LXN by sponging miR-127-5p

BACKGROUND: Our study aims to investigate the role and mechanism of circular RNA_0002715 (circ_0002715) in osteoarthritis (OA) progression. METHODS: IL-1β-induced CHON-001 cells were used to mimic OA cell model. Circ_0002715, microRNA (miR)-127-5p and Latexin (LXN) expression was detected by quantit...

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Detalles Bibliográficos
Autores principales: Liu, Hongbo, Zhao, Hongxia, Huang, Yin, Lei, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10031964/
https://www.ncbi.nlm.nih.gov/pubmed/36949500
http://dx.doi.org/10.1186/s13018-023-03638-3