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Brain-derived neurotrophic factor released from blood platelets prevents dendritic atrophy of lesioned adult central nervous system neurons

In humans and other primates, blood platelets contain high concentrations of brain-derived neurotrophic factor due to the expression of the BDNF gene in megakaryocytes. By contrast, mice, typically used to investigate the impact of CNS lesions, have no demonstrable levels of brain-derived neurotroph...

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Detalles Bibliográficos
Autores principales: Want, Andrew, Nan, Xinsheng, Kokkali, Eirini, Barde, Yves-Alain, Morgan, James E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032030/
https://www.ncbi.nlm.nih.gov/pubmed/36970044
http://dx.doi.org/10.1093/braincomms/fcad046