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Brain-derived neurotrophic factor released from blood platelets prevents dendritic atrophy of lesioned adult central nervous system neurons
In humans and other primates, blood platelets contain high concentrations of brain-derived neurotrophic factor due to the expression of the BDNF gene in megakaryocytes. By contrast, mice, typically used to investigate the impact of CNS lesions, have no demonstrable levels of brain-derived neurotroph...
Autores principales: | Want, Andrew, Nan, Xinsheng, Kokkali, Eirini, Barde, Yves-Alain, Morgan, James E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032030/ https://www.ncbi.nlm.nih.gov/pubmed/36970044 http://dx.doi.org/10.1093/braincomms/fcad046 |
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