Cargando…

Systemic glucose-insulin-potassium reduces skeletal muscle injury, kidney injury, and pain in a murine ischaemia-reperfusion model

AIMS: Glucose-insulin-potassium (GIK) is protective following cardiac myocyte ischaemia-reperfusion (IR) injury, however the role of GIK in protecting skeletal muscle from IR injury has not been evaluated. Given the similar mechanisms by which cardiac and skeletal muscle sustain an IR injury, we hyp...

Descripción completa

Detalles Bibliográficos
Autores principales: Buchalter, Daniel B., Kirby, David J., Anil, Utkarsh, Konda, Sanjit R., Leucht, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032225/
https://www.ncbi.nlm.nih.gov/pubmed/37051831
http://dx.doi.org/10.1302/2046-3758.123.BJR-2022-0312.R1