Antidepressant and Neuroprotective Effects of 3-Hydroxy Paroxetine, an Analog of Paroxetine in Rats

BACKGROUND: Paroxetine (PX) is a widely used antidepressant with side effects such as weakness, dizziness, and trouble sleeping. In search of novel compounds with better efficacy and fewer side effects, we synthesized 3HPX, a hydroxylated analog of PX, and compared the 2 in silico for their pharmaco...

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Detalles Bibliográficos
Autores principales: Hernández-Arrambide, Pedro Efraín, Carrasco-Carballo, Alan, Parra, Irving, Chamorro-Arenas, Delfino, Martínez, Isabel, Luna, Félix, Sartillo-Piscil, Fernando, Tizabi, Yousef, Mendieta, Liliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Regular Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032298/
https://www.ncbi.nlm.nih.gov/pubmed/36433759
http://dx.doi.org/10.1093/ijnp/pyac077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032298/
https://www.ncbi.nlm.nih.gov/pubmed/36433759
http://dx.doi.org/10.1093/ijnp/pyac077

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