Network-informed discovery of multidrug combinations for ERα+/HER2-/PI3Kα-mutant breast cancer

Breast cancer is a persistent threat to women worldwide. A large proportion of breast cancers are dependent on the estrogen receptor α (ERα) for tumor progression. Therefore, targeting ERα with antagonists, such as tamoxifen, or estrogen deprivation by aromatase inhibitors remain standard therapies...

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Detalles Bibliográficos
Autores principales: Hany, Dina, Zoetemelk, Marloes, Bhattacharya, Kaushik, Nowak-Sliwinska, Patrycja, Picard, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032341/
https://www.ncbi.nlm.nih.gov/pubmed/36869202
http://dx.doi.org/10.1007/s00018-023-04730-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032341/
https://www.ncbi.nlm.nih.gov/pubmed/36869202
http://dx.doi.org/10.1007/s00018-023-04730-x

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