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Host Cell Rap1b mediates cAMP-dependent invasion by Trypanosoma cruzi

Trypanosoma cruzi cAMP-mediated invasion has long been described, however, the detailed mechanism of action of the pathway activated by this cyclic nucleotide still remains unknown. We have recently demonstrated a crucial role for Epac in the cAMP-mediated invasion of the host cell. In this work, we...

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Detalles Bibliográficos
Autores principales: Ferri, Gabriel, Musikant, Daniel, Edreira, Martin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032529/
https://www.ncbi.nlm.nih.gov/pubmed/36897926
http://dx.doi.org/10.1371/journal.pntd.0011191