Cargando…

Pneumolysin as a target for new therapies against pneumococcal infections: A systematic review

BACKGROUND: This systematic review evaluates pneumolysin (PLY) as a target for new treatments against pneumococcal infections. Pneumolysin is one of the main virulence factors produced by all types of pneumococci. This toxin (53 kDa) is a highly conserved protein that binds to cholesterol in eukaryo...

Descripción completa

Detalles Bibliográficos
Autores principales: Cima Cabal, María Dolores, Molina, Felipe, López-Sánchez, José Ignacio, Pérez-Santín, Efrén, del Mar García-Suárez, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032530/
https://www.ncbi.nlm.nih.gov/pubmed/36947540
http://dx.doi.org/10.1371/journal.pone.0282970