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Phosphorylation at Ser289 Enhances the Oligomerization of Tau Repeat R2
[Image: see text] In tauopathies such as Alzheimer’s disease (AD), aberrant phosphorylation causes the dissociation of tau proteins from microtubules. The dissociated tau then aggregates into sequent forms from soluble oligomers to paired helical filaments and insoluble neurofibrillary tangles (NFTs...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032562/ https://www.ncbi.nlm.nih.gov/pubmed/36786552 http://dx.doi.org/10.1021/acs.jcim.2c01597 |