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Phosphorylation at Ser289 Enhances the Oligomerization of Tau Repeat R2

[Image: see text] In tauopathies such as Alzheimer’s disease (AD), aberrant phosphorylation causes the dissociation of tau proteins from microtubules. The dissociated tau then aggregates into sequent forms from soluble oligomers to paired helical filaments and insoluble neurofibrillary tangles (NFTs...

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Detalles Bibliográficos
Autores principales:	Man, Viet Hoang, He, Xibing, Han, Fengyang, Cai, Lianjin, Wang, Luxuan, Niu, Taoyu, Zhai, Jingchen, Ji, Beihong, Gao, Jie, Wang, Junmei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032562/ https://www.ncbi.nlm.nih.gov/pubmed/36786552 http://dx.doi.org/10.1021/acs.jcim.2c01597

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