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Molecular Modeling Study of a Receptor–Orthosteric Ligand–Allosteric Modulator Signaling Complex
[Image: see text] Allosteric modulators (AMs) are considered as a perpetual hotspot in research for their higher selectivity and various effects on orthosteric ligands (OL). They are classified in terms of their functionalities as positive, negative, or silent allosteric modulators (PAM, NAM, or SAM...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032570/ https://www.ncbi.nlm.nih.gov/pubmed/36692197 http://dx.doi.org/10.1021/acschemneuro.2c00554 |