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Molecular Modeling Study of a Receptor–Orthosteric Ligand–Allosteric Modulator Signaling Complex

[Image: see text] Allosteric modulators (AMs) are considered as a perpetual hotspot in research for their higher selectivity and various effects on orthosteric ligands (OL). They are classified in terms of their functionalities as positive, negative, or silent allosteric modulators (PAM, NAM, or SAM...

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Detalles Bibliográficos
Autores principales: Jiang, Chen, He, Xibing, Wang, Yuanqiang, Chen, Chih-Jung, Othman, Yasmin, Hao, Yixuan, Yuan, Jiayi, Xie, Xiang-Qun, Feng, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032570/
https://www.ncbi.nlm.nih.gov/pubmed/36692197
http://dx.doi.org/10.1021/acschemneuro.2c00554