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The telomerase reverse transcriptase elongates reversed replication forks at telomeric repeats
The telomerase reverse transcriptase elongates telomeres to prevent replicative senescence. This process requires exposure of the 3′-end, which is thought to occur when two sister telomeres are generated at replication completion. Using two-dimensional agarose gel electrophoresis (2D-gels) and elect...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032592/ https://www.ncbi.nlm.nih.gov/pubmed/36947627 http://dx.doi.org/10.1126/sciadv.adf2011 |