The telomerase reverse transcriptase elongates reversed replication forks at telomeric repeats

The telomerase reverse transcriptase elongates telomeres to prevent replicative senescence. This process requires exposure of the 3′-end, which is thought to occur when two sister telomeres are generated at replication completion. Using two-dimensional agarose gel electrophoresis (2D-gels) and elect...

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Detalles Bibliográficos
Autores principales: Huda, Armela, Arakawa, Hiroshi, Mazzucco, Giulia, Galli, Martina, Petrocelli, Valentina, Casola, Stefano, Chen, Lu, Doksani, Ylli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032592/
https://www.ncbi.nlm.nih.gov/pubmed/36947627
http://dx.doi.org/10.1126/sciadv.adf2011

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