Loss of neuronal Tet2 enhances hippocampal-dependent cognitive function

DNA methylation has emerged as a critical modulator of neuronal plasticity and cognitive function. Notwithstanding, the role of enzymes that demethylate DNA remain to be fully explored. Here, we report that loss of ten-eleven translocation methylcytosine dioxygenase 2 (Tet2), which catalyzes oxidati...

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Detalles Bibliográficos
Autores principales: Pratt, Karishma J.B., Shea, Jeremy M., Remesal-Gomez, Laura, Bieri, Gregor, Smith, Lucas K., Couthouis, Julien, Chen, Christopher P., Roy, Irena J., Gontier, Geraldine, Villeda, Saul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032941/
https://www.ncbi.nlm.nih.gov/pubmed/36351399
http://dx.doi.org/10.1016/j.celrep.2022.111612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10032941/
https://www.ncbi.nlm.nih.gov/pubmed/36351399
http://dx.doi.org/10.1016/j.celrep.2022.111612

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