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Defibrotide mitigates endothelial cell injury induced by plasmas from patients with COVID-19 and related vasculopathies

BACKGROUND AND OBJECTIVES: COVID-19 progression is characterized by systemic small vessel arterial and venous thrombosis. Microvascular endothelial cell (MVEC) activation and injury, platelet activation, and histopathologic features characteristic of acute COVID-19 also describe certain thrombotic m...

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Detalles Bibliográficos
Autores principales: Elhadad, Sonia, Redmond, David, Tan, Adrian, Huang, Jenny, Rodriguez, Beatriz Lorenzo, Racine-Brzostek, Sabrina E., Subrahmanian, Sandeep, Ahamed, Jasimuddin, Laurence, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033153/
https://www.ncbi.nlm.nih.gov/pubmed/37001283
http://dx.doi.org/10.1016/j.thromres.2023.03.009