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Defibrotide mitigates endothelial cell injury induced by plasmas from patients with COVID-19 and related vasculopathies
BACKGROUND AND OBJECTIVES: COVID-19 progression is characterized by systemic small vessel arterial and venous thrombosis. Microvascular endothelial cell (MVEC) activation and injury, platelet activation, and histopathologic features characteristic of acute COVID-19 also describe certain thrombotic m...
Autores principales: | Elhadad, Sonia, Redmond, David, Tan, Adrian, Huang, Jenny, Rodriguez, Beatriz Lorenzo, Racine-Brzostek, Sabrina E., Subrahmanian, Sandeep, Ahamed, Jasimuddin, Laurence, Jeffrey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033153/ https://www.ncbi.nlm.nih.gov/pubmed/37001283 http://dx.doi.org/10.1016/j.thromres.2023.03.009 |
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