Mechanisms of Obesity-Induced Changes in Pharmacokinetics of IgG in Rats

PURPOSE: To evaluate how obesity affects the pharmacokinetics of human IgG following subcutaneous (SC) and intravenous (IV) administration to rats and the homeostasis of endogenous rat IgG. METHODS: Differences in body weight and size, body composition, and serum concentration of endogenous rat IgG...

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Detalles Bibliográficos
Autores principales: Gao, Xizhe, Sheng, Yi-Hua, Yu, Sijia, Li, Jiadong, Rosa, Raymond, Girgis, Simone, Guo, Tiffany, Brunetti, Luigi, Kagan, Leonid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033182/
https://www.ncbi.nlm.nih.gov/pubmed/36949370
http://dx.doi.org/10.1007/s11095-023-03496-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033182/
https://www.ncbi.nlm.nih.gov/pubmed/36949370
http://dx.doi.org/10.1007/s11095-023-03496-y

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