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Group 3 innate lymphoid cells secret neutrophil chemoattractants and are insensitive to glucocorticoid via aberrant GR phosphorylation

BACKGROUND: Patients with neutrophil-mediated asthma have poor response to glucocorticoids. The roles and mechanisms of group 3 innate lymphoid cells (ILC3s) in inducing neutrophilic airway inflammation and glucocorticoid resistance in asthma have not been fully clarified. METHODS: ILC3s in peripher...

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Detalles Bibliográficos
Autores principales: He, Li Xiu, Yang, Ling, Liu, Ting, Li, Yi Na, Huang, Ting Xuan, Zhang, Lan Lan, Luo, Jian, Liu, Chun Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033286/
https://www.ncbi.nlm.nih.gov/pubmed/36949482
http://dx.doi.org/10.1186/s12931-023-02395-5