Combination Ad26.RSV.preF/preF protein vaccine induces superior protective immunity compared with individual vaccine components in preclinical models

Respiratory syncytial virus (RSV) is a leading cause of severe respiratory disease for which no licensed vaccine is available. We have previously shown that a prefusion (preF) conformation-stabilized RSV F protein antigen and an adenoviral vector encoding RSV preF protein (Ad26.RSV.preF) are immunog...

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Detalles Bibliográficos
Autores principales: Saeland, Eirikur, van der Fits, Leslie, Bolder, Renske, Heemskerk-van der Meer, Marjolein, Drijver, Joke, van Polanen, Yolinda, Vaneman, Cornelis, Tettero, Lisanne, Cox, Freek, Serroyen, Jan, Jorgensen, Matthew J., Langedijk, Johannes P. M., Schuitemaker, Hanneke, Callendret, Benoit, Zahn, Roland C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033289/
https://www.ncbi.nlm.nih.gov/pubmed/36949051
http://dx.doi.org/10.1038/s41541-023-00637-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033289/
https://www.ncbi.nlm.nih.gov/pubmed/36949051
http://dx.doi.org/10.1038/s41541-023-00637-7

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