The C-terminal domains of ADAMTS1 contain exosites involved in its proteoglycanase activity

A disintegrin-like and metalloproteinase with thrombospondin type 1 motifs (ADAMTS1) is a protease involved in fertilization, cancer, cardiovascular development, and thoracic aneurysms. Proteoglycans such as versican and aggrecan have been identified as ADAMTS1 substrates, and Adamts1 ablation in mi...

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Detalles Bibliográficos
Autores principales: Minns, Alexander Frederick, Qi, Yawei, Yamamoto, Kazuhiro, Lee, Karen, Ahnström, Josefin, Santamaria, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033314/
https://www.ncbi.nlm.nih.gov/pubmed/36813235
http://dx.doi.org/10.1016/j.jbc.2023.103048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033314/
https://www.ncbi.nlm.nih.gov/pubmed/36813235
http://dx.doi.org/10.1016/j.jbc.2023.103048

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