Cargando…
The C-terminal domains of ADAMTS1 contain exosites involved in its proteoglycanase activity
A disintegrin-like and metalloproteinase with thrombospondin type 1 motifs (ADAMTS1) is a protease involved in fertilization, cancer, cardiovascular development, and thoracic aneurysms. Proteoglycans such as versican and aggrecan have been identified as ADAMTS1 substrates, and Adamts1 ablation in mi...
Autores principales: | Minns, Alexander Frederick, Qi, Yawei, Yamamoto, Kazuhiro, Lee, Karen, Ahnström, Josefin, Santamaria, Salvatore |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033314/ https://www.ncbi.nlm.nih.gov/pubmed/36813235 http://dx.doi.org/10.1016/j.jbc.2023.103048 |
Ejemplares similares
-
Exosites in Hypervariable Loops of ADAMTS Spacer Domains control Substrate Recognition and Proteolysis
por: Santamaria, Salvatore, et al.
Publicado: (2019) -
Exosite inhibition of ADAMTS-5 by a glycoconjugated arylsulfonamide
por: Santamaria, Salvatore, et al.
Publicado: (2021) -
The Role of ADAMTS Proteoglycanases in Thoracic Aortic Disease
por: Kemberi, Marsioleda, et al.
Publicado: (2023) -
Antibody-based exosite inhibitors of ADAMTS-5 (aggrecanase-2)
por: Santamaria, Salvatore, et al.
Publicado: (2015) -
ADAMTS proteoglycanases in the physiological and pathological central nervous system
por: Lemarchant, Sighild, et al.
Publicado: (2013)