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Selective PPARγ modulator diosmin improves insulin sensitivity and promotes browning of white fat

Peroxisome proliferator–activated receptor γ (PPARγ) is a master regulator of adipocyte differentiation, glucolipid metabolism, and inflammation. Thiazolidinediones are PPARγ full agonists with potent insulin-sensitizing effects, whereas their oral usage is restricted because of unwanted side effect...

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Detalles Bibliográficos
Autores principales: Yu, Jian, Hu, Yepeng, Sheng, Maozheng, Gao, Mingyuan, Guo, Wenxiu, Zhang, Zhe, Wang, Dongmei, Wu, Xia, Li, Jin, Chen, Yantao, Zhao, Wenjun, Liu, Caizhi, Cui, Xiangdi, Chen, Xin, Zhao, Cheng, Chen, Huang, Xiao, Junjie, Chen, Shijie, Luo, Cheng, Xu, Lingyan, Gu, Xuejiang, Ma, Xinran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033317/
https://www.ncbi.nlm.nih.gov/pubmed/36841479
http://dx.doi.org/10.1016/j.jbc.2023.103059