Pharmacogenetic profiling via genome sequencing in children with medical complexity

BACKGROUND: Children with medical complexity (CMC) are a priority pediatric population, with high resource use and associated costs. Genome-wide sequencing is increasingly organized for CMC early in life as a diagnostic test. Polypharmacy becomes common as CMC age. Clinically relevant pharmacogeneti...

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Detalles Bibliográficos
Autores principales: Pan, Amy, Scodellaro, Sierra, Khan, Tayyaba, Ushcatz, Inna, Wu, Wendy, Curtis, Meredith, Cohen, Eyal, Cohn, Ronald D., Hayeems, Robin Z., Meyn, M. Stephen, Orkin, Julia, Otal, Jaskiran, Reuter, Miriam S., Walker, Susan, Scherer, Stephen W., Marshall, Christian R., Cohn, Iris, Costain, Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Clinical Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033400/
https://www.ncbi.nlm.nih.gov/pubmed/36167815
http://dx.doi.org/10.1038/s41390-022-02313-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033400/
https://www.ncbi.nlm.nih.gov/pubmed/36167815
http://dx.doi.org/10.1038/s41390-022-02313-3

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