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Decreased expression of hypoxia-inducible factor 1α (HIF-1α) in cord blood monocytes under anoxia

BACKGROUND: Infections are a major cause for morbidity and mortality in neonates; however, the underling mechanisms for increased infection susceptibility are incompletely understood. Hypoxia, which is present in inflamed tissues, has been identified as an important activation signal for innate immu...

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Detalles Bibliográficos
Autores principales: Schlegel, Christiane, Liu, Kai, Spring, Bärbel, Dietz, Stefanie, Poets, Christian F., Hudalla, Hannes, Lajqi, Trim, Köstlin-Gille, Natascha, Gille, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033401/
https://www.ncbi.nlm.nih.gov/pubmed/35906309
http://dx.doi.org/10.1038/s41390-022-02193-7