Cargando…

Decreased expression of hypoxia-inducible factor 1α (HIF-1α) in cord blood monocytes under anoxia

BACKGROUND: Infections are a major cause for morbidity and mortality in neonates; however, the underling mechanisms for increased infection susceptibility are incompletely understood. Hypoxia, which is present in inflamed tissues, has been identified as an important activation signal for innate immu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schlegel, Christiane, Liu, Kai, Spring, Bärbel, Dietz, Stefanie, Poets, Christian F., Hudalla, Hannes, Lajqi, Trim, Köstlin-Gille, Natascha, Gille, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2022
Materias:	Basic Science Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033401/ https://www.ncbi.nlm.nih.gov/pubmed/35906309 http://dx.doi.org/10.1038/s41390-022-02193-7

Ejemplares similares

HIF-1α-Deficiency in Myeloid Cells Leads to a Disturbed Accumulation of Myeloid Derived Suppressor Cells (MDSC) During Pregnancy and to an Increased Abortion Rate in Mice
por: Köstlin-Gille, Natascha, et al.
Publicado: (2019)

Different probiotic strains alter human cord blood monocyte responses
por: Rückle, Xenia, et al.
Publicado: (2022)

Depletion of Ly6G-Expressing Neutrophilic Cells Leads to Altered Peripheral T-Cell Homeostasis and Thymic Development in Neonatal Mice
por: Rühle, Jessica, et al.
Publicado: (2023)

Gut Microbiota-Derived Small Extracellular Vesicles Endorse Memory-like Inflammatory Responses in Murine Neutrophils
por: Lajqi, Trim, et al.
Publicado: (2022)

Training vs. Tolerance: The Yin/Yang of the Innate Immune System
por: Lajqi, Trim, et al.
Publicado: (2023)

Group B streptococci infection model shows decreased regulatory capacity of cord blood cells
por: Molnar, Kriszta, et al.
Publicado: (2022)

Expression of immune checkpoint molecules on adult and neonatal T-cells
por: Dietz, Stefanie, et al.
Publicado: (2022)

Granulocytic Myeloid-Derived Suppressor Cells (GR-MDSC) in Breast Milk (BM); GR-MDSC Accumulate in Human BM and Modulate T-Cell and Monocyte Function
por: Köstlin, Natascha, et al.
Publicado: (2018)

Granulocytic myeloid-derived suppressor cells expand in cord blood and human pregnancy and modulate T cell responses
por: Köstlin, Natascha, et al.
Publicado: (2014)

Granulocytic Myeloid-Derived Suppressor Cells in Breast Milk (BM-MDSC) Correlate with Gestational Age and Postnatal Age and Are Influenced by Infant’s Sex
por: Köstlin-Gille, Natascha, et al.
Publicado: (2020)

Myeloid-Derived Suppressor Cells in Pregnancy and the Neonatal Period
por: Köstlin-Gille, Natascha, et al.
Publicado: (2020)

Human Leucocyte Antigen G and Murine Qa-2 Are Critical for Myeloid Derived Suppressor Cell Expansion and Activation and for Successful Pregnancy Outcome
por: Dietz, Stefanie, et al.
Publicado: (2022)

The Role of Microbiota in Neutrophil Regulation and Adaptation in Newborns
por: Lajqi, Trim, et al.
Publicado: (2020)

Metalloproteinases TACE and MMP-9 Differentially Regulate Death Factors on Adult and Neonatal Monocytes After Infection with Escherichia coli
por: Dreschers, Stephan, et al.
Publicado: (2019)

Early initiation of antibiotic therapy and short-term outcomes in preterm infants: a single-centre retrospective cohort analysis
por: Köstlin-Gille, Natascha, et al.
Publicado: (2023)

LPS Induces Opposing Memory-like Inflammatory Responses in Mouse Bone Marrow Neutrophils
por: Lajqi, Trim, et al.
Publicado: (2021)

Impact of early antibiotic exposure on the risk of colonization with potential pathogens in very preterm infants: a retrospective cohort analysis
por: Bubser, Caren, et al.
Publicado: (2022)

Memory-Like Responses of Brain Microglia Are Controlled by Developmental State and Pathogen Dose
por: Lajqi, Trim, et al.
Publicado: (2020)

The Role of the Pathogen Dose and PI3Kγ in Immunometabolic Reprogramming of Microglia for Innate Immune Memory
por: Lajqi, Trim, et al.
Publicado: (2021)

Evaluation of the effects of pregabalin on chondrocyte proliferation and CHAD, HIF-1α, and COL2A1 gene expression
por: Sirin, Duygu Yasar, et al.
Publicado: (2018)

L-Arginine Modulates Neonatal Leukocyte Recruitment in a Gestational Age-Dependent Manner
por: Fitterer, Raphaela, et al.
Publicado: (2020)

Memory-Like Inflammatory Responses of Microglia to Rising Doses of LPS: Key Role of PI3Kγ
por: Lajqi, Trim, et al.
Publicado: (2019)

Cryptochromes Suppress HIF1α in Muscles
por: Vaughan, Megan E., et al.
Publicado: (2020)

2194: Effects of anoxia on viability and differentiation of human cardiosphere-derived cells
por: Khanjyan, Michael, et al.
Publicado: (2018)

Coxiella burnetii Affects HIF1α Accumulation and HIF1α Target Gene Expression
por: Hayek, Inaya, et al.
Publicado: (2022)

Molecular characterization of mudskipper (Boleophthalmus pectinirostris) hypoxia-inducible factor-1α (HIF-1α) and analysis of its function in monocytes/macrophages
por: Guan, Feng, et al.
Publicado: (2017)

Regulation of glycolysis in brown adipocytes by HIF-1α
por: Basse, Astrid L., et al.
Publicado: (2017)

Expression of multidrug resistance protein P-glycoprotein in correlation with markers of hypoxia (HIF-1α, EPO, EPO-R) in invasive breast cancer with metastasis to lymph nodes
por: Badowska-Kozakiewicz, Anna M., et al.
Publicado: (2016)

Sun and survival with Hif1α
por: Tuma, Rabiya S.
Publicado: (2005)

HIF-1α in cerebral ischemia
por: Dong, Peiliang, et al.
Publicado: (2022)

Endothelial Cell HIF-1α and HIF-2α Differentially Regulate Metastatic Success
por: Branco-Price, Cristina, et al.
Publicado: (2012)

HIF1α and HIF2α Exert Distinct Nutrient Preferences in Renal Cells
por: Arreola, Alexandra, et al.
Publicado: (2014)

HIF-1α and HIF-2α Differently Regulate the Radiation Sensitivity of NSCLC Cells
por: Moreno Roig, Eloy, et al.
Publicado: (2019)

HIF-1α is Overexpressed in Odontogenic Keratocyst Suggesting Activation of HIF-1α and NOTCH1 Signaling Pathways
por: Miranda da Costa, Natacha Malu, et al.
Publicado: (2019)

HIF-transcribed p53 chaperones HIF-1α
por: Madan, Esha, et al.
Publicado: (2019)

Expression of Hypoxia-Inducible Factor 1α (HIF-1α) and Genes of Related Pathways in Altered Gravity
por: Vogel, Johannes, et al.
Publicado: (2019)

The role of AMPKα2 in cardiomyocytes anoxia/reoxygenation injury mediated by Cl(-)
por: Liu, Dan, et al.
Publicado: (2012)

Expression of sterile-α and armadillo motif containing protein (SARM) in rheumatoid arthritis monocytes correlates with TLR2-induced IL-1β and disease activity
por: Thwaites, Ryan S, et al.
Publicado: (2021)

Microbiological analyses of nasally guided catheters after less invasive surfactant administration – a pilot study
por: Maiwald, Christian A., et al.
Publicado: (2020)

Hif-1α and Hif-2α synergize to suppress AML development but are dispensable for disease maintenance
por: Vukovic, Milica, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ce8ggsf22btauimnfvlpkcmc7c