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Catalytic asymmetric synthesis of cannabinoids and menthol from neral

The selective conversion of natural or synthetic neral to (1R,6S)-trans-isopiperitenol would enable and expedite sustainable routes to menthol(1,2) and cannabinoids(3–5). However, this reaction has been considered impossible because its product is more reactive to the required acid catalysts than it...

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Detalles Bibliográficos
Autores principales: Grimm, Joyce A. A., Zhou, Hui, Properzi, Roberta, Leutzsch, Markus, Bistoni, Giovanni, Nienhaus, Johanna, List, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033408/
https://www.ncbi.nlm.nih.gov/pubmed/36859552
http://dx.doi.org/10.1038/s41586-023-05747-9