Autoregulation of GPCR signalling through the third intracellular loop

The third intracellular loop (ICL3) of the G protein-coupled receptor (GPCR) fold is important for the signal transduction process downstream of receptor activation(1–3). Despite this, the lack of a defined structure of ICL3, combined with its high sequence divergence among GPCRs, complicates charac...

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Detalles Bibliográficos
Autores principales: Sadler, Fredrik, Ma, Ning, Ritt, Michael, Sharma, Yatharth, Vaidehi, Nagarajan, Sivaramakrishnan, Sivaraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033409/
https://www.ncbi.nlm.nih.gov/pubmed/36890236
http://dx.doi.org/10.1038/s41586-023-05789-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033409/
https://www.ncbi.nlm.nih.gov/pubmed/36890236
http://dx.doi.org/10.1038/s41586-023-05789-z

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