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Autoregulation of GPCR signalling through the third intracellular loop
The third intracellular loop (ICL3) of the G protein-coupled receptor (GPCR) fold is important for the signal transduction process downstream of receptor activation(1–3). Despite this, the lack of a defined structure of ICL3, combined with its high sequence divergence among GPCRs, complicates charac...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033409/ https://www.ncbi.nlm.nih.gov/pubmed/36890236 http://dx.doi.org/10.1038/s41586-023-05789-z |