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The structural basis for HIV-1 Vif antagonism of human APOBEC3G
The APOBEC3 (A3) proteins are host antiviral cellular proteins that hypermutate the viral genome of diverse viral families. In retroviruses, this process requires A3 packaging into viral particles(1–4). The lentiviruses encode a protein, Vif, that antagonizes A3 family members by targeting them for...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033410/ https://www.ncbi.nlm.nih.gov/pubmed/36754086 http://dx.doi.org/10.1038/s41586-023-05779-1 |