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The structural basis for HIV-1 Vif antagonism of human APOBEC3G

The APOBEC3 (A3) proteins are host antiviral cellular proteins that hypermutate the viral genome of diverse viral families. In retroviruses, this process requires A3 packaging into viral particles(1–4). The lentiviruses encode a protein, Vif, that antagonizes A3 family members by targeting them for...

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Detalles Bibliográficos
Autores principales: Li, Yen-Li, Langley, Caroline A., Azumaya, Caleigh M., Echeverria, Ignacia, Chesarino, Nicholas M., Emerman, Michael, Cheng, Yifan, Gross, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033410/
https://www.ncbi.nlm.nih.gov/pubmed/36754086
http://dx.doi.org/10.1038/s41586-023-05779-1

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