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Overexpression of CHAF1A is associated with poor prognosis, tumor immunosuppressive microenvironment and treatment resistance

Background: As distinct marker of proliferating cells, chromatin assembly factor-1 (CAF-1) was critical in DNA replication. However, there is paucity information about the clinical significance, functions and co-expressed gene network of CHAF1A, the major subunit in CAF-1, in cancer. Methods: Bioinf...

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Detalles Bibliográficos
Autores principales: Sun, Xia, Ma, Qiushuang, Cheng, Yahong, Huang, Huangwei, Qin, Jing, Zhang, Mengchen, Qu, Sifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033519/
https://www.ncbi.nlm.nih.gov/pubmed/36968583
http://dx.doi.org/10.3389/fgene.2023.1108004