Analysis of 2′-hydroxyflavanone (2HF) in mouse whole blood by HPLC–MS/MS for the determination of pharmacokinetic parameters

Given the lack of investments, structure, and difficulty of metabolite isolation, promising natural product studies do not progress to preclinical studies, such as pharmacokinetics. 2′-Hydroxyflavanone (2HF) is a flavonoid that has shown promising results in different types of cancer and leishmanias...

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Detalles Bibliográficos
Autores principales: Gervazoni, Luiza F. O., Gonçalves-Ozorio, Gabriella, Ferreira-Paes, Taiana, Silva, Aline C. A., Silveira, Gabriel P. E., Pereira, Heliana M., Pinto, Douglas P., Cunha-Junior, Edézio F., Almeida-Amaral, Elmo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033538/
https://www.ncbi.nlm.nih.gov/pubmed/36970405
http://dx.doi.org/10.3389/fchem.2023.1016193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033538/
https://www.ncbi.nlm.nih.gov/pubmed/36970405
http://dx.doi.org/10.3389/fchem.2023.1016193

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