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Analysis of 2′-hydroxyflavanone (2HF) in mouse whole blood by HPLC–MS/MS for the determination of pharmacokinetic parameters
Given the lack of investments, structure, and difficulty of metabolite isolation, promising natural product studies do not progress to preclinical studies, such as pharmacokinetics. 2′-Hydroxyflavanone (2HF) is a flavonoid that has shown promising results in different types of cancer and leishmanias...
Autores principales: | Gervazoni, Luiza F. O., Gonçalves-Ozorio, Gabriella, Ferreira-Paes, Taiana, Silva, Aline C. A., Silveira, Gabriel P. E., Pereira, Heliana M., Pinto, Douglas P., Cunha-Junior, Edézio F., Almeida-Amaral, Elmo E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033538/ https://www.ncbi.nlm.nih.gov/pubmed/36970405 http://dx.doi.org/10.3389/fchem.2023.1016193 |
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