A pan-variant mRNA-LNP T cell vaccine protects HLA transgenic mice from mortality after infection with SARS-CoV-2 Beta

Licensed COVID-19 vaccines ameliorate viral infection by inducing production of neutralizing antibodies that bind the SARS-CoV-2 Spike protein and inhibit viral cellular entry. However, the clinical effectiveness of these vaccines is transitory as viral variants escape antibody neutralization. Effec...

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Detalles Bibliográficos
Autores principales: Carter, Brandon, Huang, Pinghan, Liu, Ge, Liang, Yuejin, Lin, Paulo J. C., Peng, Bi-Hung, McKay, Lindsay G. A., Dimitrakakis, Alexander, Hsu, Jason, Tat, Vivian, Saenkham-Huntsinger, Panatda, Chen, Jinjin, Kaseke, Clarety, Gaiha, Gaurav D., Xu, Qiaobing, Griffiths, Anthony, Tam, Ying K., Tseng, Chien-Te K., Gifford, David K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033589/
https://www.ncbi.nlm.nih.gov/pubmed/36969239
http://dx.doi.org/10.3389/fimmu.2023.1135815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033589/
https://www.ncbi.nlm.nih.gov/pubmed/36969239
http://dx.doi.org/10.3389/fimmu.2023.1135815

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