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Oxypurinol protects renal ischemia/reperfusion injury via heme oxygenase-1 induction

Renal ischemia/reperfusion (I/R) injury is a major cause of acute kidney injury (AKI) by increasing oxidative stress, inflammatory responses, and tubular cell death. Oxypurinol, an active metabolite of allopurinol, is a potent anti-inflammatory and antioxidant agent. To investigate the therapeutic p...

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Detalles Bibliográficos
Autores principales: Kang, Hye Bin, Lim, Chae Kyu, Kim, Jongwan, Han, Sang Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033620/
https://www.ncbi.nlm.nih.gov/pubmed/36968831
http://dx.doi.org/10.3389/fmed.2023.1030577