USP10 deubiquitinates RUNX1 and promotes proneural-to-mesenchymal transition in glioblastoma

The mesenchymal (MES) subtype of glioblastoma (GBM) is a highly aggressive, malignant and proliferative cancer that is resistant to chemotherapy. Runt-related transcription factor 1 (RUNX1) was shown to support MES GBM, however, its underlying mechanisms are unclear. Here, we identified USP10 as a d...

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Detalles Bibliográficos
Autores principales: Qiu, Wenjin, Xiao, Zumu, Yang, Yushi, Jiang, Lishi, Song, Shibin, Qi, Xiaolan, Chen, Yimin, Yang, Hua, Liu, Jian, Chu, Liangzhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033651/
https://www.ncbi.nlm.nih.gov/pubmed/36949071
http://dx.doi.org/10.1038/s41419-023-05734-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033651/
https://www.ncbi.nlm.nih.gov/pubmed/36949071
http://dx.doi.org/10.1038/s41419-023-05734-y

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