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BrainGENIE: The Brain Gene Expression and Network Imputation Engine

In vivo experimental analysis of human brain tissue poses substantial challenges and ethical concerns. To address this problem, we developed a computational method called the Brain Gene Expression and Network-Imputation Engine (BrainGENIE) that leverages peripheral-blood transcriptomes to predict br...

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Detalles Bibliográficos
Autores principales: Hess, Jonathan L., Quinn, Thomas P., Zhang, Chunling, Hearn, Gentry C., Chen, Samuel, Kong, Sek Won, Cairns, Murray, Tsuang, Ming T., Faraone, Stephen V., Glatt, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033657/
https://www.ncbi.nlm.nih.gov/pubmed/36949060
http://dx.doi.org/10.1038/s41398-023-02390-w