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BrainGENIE: The Brain Gene Expression and Network Imputation Engine
In vivo experimental analysis of human brain tissue poses substantial challenges and ethical concerns. To address this problem, we developed a computational method called the Brain Gene Expression and Network-Imputation Engine (BrainGENIE) that leverages peripheral-blood transcriptomes to predict br...
Autores principales: | Hess, Jonathan L., Quinn, Thomas P., Zhang, Chunling, Hearn, Gentry C., Chen, Samuel, Kong, Sek Won, Cairns, Murray, Tsuang, Ming T., Faraone, Stephen V., Glatt, Stephen J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033657/ https://www.ncbi.nlm.nih.gov/pubmed/36949060 http://dx.doi.org/10.1038/s41398-023-02390-w |
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