Insights into receptor structure and dynamics at the surface of living cells

Evaluating protein structures in living cells remains a challenge. Here, we investigate Interleukin-4 receptor alpha (IL-4Rα) into which the non-canonical amino acid bicyclo[6.1.0]nonyne-lysine (BCNK) is incorporated by genetic code expansion. Bioorthogonal click labeling is performed with tetrazine...

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Detalles Bibliográficos
Autores principales: Steiert, Frederik, Schultz, Peter, Höfinger, Siegfried, Müller, Thomas D., Schwille, Petra, Weidemann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033668/
https://www.ncbi.nlm.nih.gov/pubmed/36949079
http://dx.doi.org/10.1038/s41467-023-37284-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033668/
https://www.ncbi.nlm.nih.gov/pubmed/36949079
http://dx.doi.org/10.1038/s41467-023-37284-4

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