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Insights into receptor structure and dynamics at the surface of living cells
Evaluating protein structures in living cells remains a challenge. Here, we investigate Interleukin-4 receptor alpha (IL-4Rα) into which the non-canonical amino acid bicyclo[6.1.0]nonyne-lysine (BCNK) is incorporated by genetic code expansion. Bioorthogonal click labeling is performed with tetrazine...
Autores principales: | Steiert, Frederik, Schultz, Peter, Höfinger, Siegfried, Müller, Thomas D., Schwille, Petra, Weidemann, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033668/ https://www.ncbi.nlm.nih.gov/pubmed/36949079 http://dx.doi.org/10.1038/s41467-023-37284-4 |
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