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Insights into the cellular pathophysiology of familial hemophagocytic lymphohistiocytosis

Familial hemophagocytic lymphohistiocytosis (fHLH) encompasses a group of rare inherited immune dysregulation disorders characterized by loss-of-function mutations in one of several genes involved in the assembly, exocytosis, and function of cytotoxic granules within CD8+ T cells and natural killer...

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Detalles Bibliográficos
Autores principales: Steen, Erica A., Nichols, Kim E., Meyer, Lauren K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033680/
https://www.ncbi.nlm.nih.gov/pubmed/36969228
http://dx.doi.org/10.3389/fimmu.2023.1147603